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Inhaled apomorphine, at doses up to 0.8 mg, appears safe and well tolerated by patients with Parkinsons disease, but does not result in significant improvement in wearing off periods, at the tested doses.
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Long-term complications, particularly secondary cancers, were significantly more common in patients receiving whole pelvic radiation (vs brachytherapy alone) for early-stage endometrial cancer.
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Using the SEER database, this report examined 1926 patients aged ≥ 70 years who were diagnosed with limited-stage small cell lung cancer between 1988 and 1997.
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A previously reported, industry-sponsored phase 3 trial showed improvements in progression-free survival, objective response, and a non-significant trend toward increased overall survival with panitumumab-FOLFIRI vs FOLFIRI alone for second-line wild-type KRAS metastatic colorectal cancer.
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In a survey of consecutive myeloma patients from the Mayo Clinic on hypothetical constructs with varying expectations regarding overall survival benefit, toxicity, and financial burden, it was found that the majority of patients would not choose maintenance if toxicity was more than just mild and overall survival benefit was less than 1 year.
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Use MAP instead of systolic blood pressure to guide assessment and response to treatment when measuring BP with non-invasive techniques.
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According to one study, as many as one in five children seen in the emergency department (ED) may be missed cases of physical abuse; thus, emergency physicians have a responsibility to consider abuse in the differential of every injured child. This article reviews the identification, evaluation, and management of a child with possible physical abuse.
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Administrative databases may not give an accurate representation of hospital-acquired pressure ulcer rates and may be inappropriate for use to compare hospitals and determine financial penalties.